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ICG Near Infrared Fluorescent Dyes~For in vivo imaging using near infrared fluorescent dyes~

  • FFor fLabeling with NHS esters, maleimides or through click reaction.
  • Labeling kits are available.
  • 【Contract labeling service】 Products are synthesized in our lab in Japan.

NHS series (Most commonly used method for labeling)

  • Labeling of antibodies by amide bonding.
  • Labeling kit is available.
Price
Code Name of Product Size Price Application and Note Protocol MSDS
IM104 ICG NHS ester (high purity) 1mg $698.00  For in vivo fluorescent imaging. Labeling of antibodies by amide bonding. Excitation /Emission maximum (nm): 790/830  
  • Donwload 179KB
IM105 ICG NHS ester (high purity) 5mg $2,650.00  For in vivo fluorescent imaging. Labeling of antibodies by amide bonding. Excitation /Emission maximum (nm): 790/830    
IM106 ICG NHS ester (high purity) 10mg ask us  For in vivo fluorescent imaging. Labeling of antibodies by amide bonding. Excitation /Emission maximum (nm): 790/830    

Maleimide series(Labeling the thiol groups of cysteine residues)

  • Labeling the thiol groups of cysteine residues.
  • All you have to do for the labeling is just mixing.
Price
Code Name of Product Size Price Application and Note Protocol MSDS
IM107 ICG maleimide 1mg $698.00 Labeling thiols of proteins with maleimide.    
IM108 ICG maleimide 5mg $2,180.00 Labeling thiols of proteins with maleimide.    
IM109 ICG maleimide 10mg ask us Labeling thiols of proteins with maleimide.    

CBT series

(Labeling of cysteine residues.)

Azide series

(Labeling easily through click reaction.)

Price
Code Name of Product Size Price Application and Note Protocol MSDS
IM113 ICG azide 1mg $498.00 Labeling of antibodies or other proteins through azide-alkyne cycloaddition (click reaction.)    
IM114 ICG azide 5mg $1,880.00 Labeling of antibodies or other proteins through azide-alkyne cycloaddition (click reaction.)    
IM115 ICG azide 10mg ask us Labeling of antibodies or other proteins through azide-alkyne cycloaddition (click reaction.)    

Flow Chart of contract ICG-antibody labeling service

Procedure for ordering
Ask us to inquire about price and scheduling.
Filling out the application documents and sending them by FAX
Please download all application documents and fill out them. Send us the filled-out documents by FAX:+81-11-351-1822, before send us your sample.
Sending your sample
Send us your sample and application documents to the above address. Be sure to pack the sample carefully to avoid drying, leakage or corruption of the vial. The sample should reach us by a weekday morning.
Deliverables
Work report Final products of contracted work, such as purified antibodies.

Indocyanine Green Labeling Kit

Indocyanine Green-NHS (succinimidyl ester) is near-infrared fluorescent probe that binds to amino acid residues without any condensing agents. Not only proteins or antibodies but also oligo-nucleotide with amino acid at the end can be labeled. This kit contains reagents and tools that required for the labeling for five times with Indocyanine Green-NHS and purification. One package of Indocyanine Green-NHS is optimum for the labeling of 300mg of proteins, such as IgG.

Indocyanine Green Labeling Kit
Contents of the kit
  • Indocyanine Green-NHS× 5
  • Dimethylsulfoxide500μL × 1
  • Reaction Buffer5mL × 1
  • Washing Buffer10mL × 1
  • Spin column for ultrafiltration× 5
Price
Code Name of Product Size Price Application and Note Protocol MSDS
IM118 ICG labeling kit 5times ask us ICG antibody labeling kit
  • Donwload 600KB
  • Donwload 293KB
IM134 1times    

【An example of ICG labeling】Labeling of antimicrobial peptide with NHS

Reference
Boudewijn E. Schaafsma, MD, J.Sven D. Mieog, MD, Merlijn Hutteman, MSc, Joost R. van der Vorst, MD, Peter J.K. Kuppen, PhD, Clemens W.G.M. Löwik, PhD, John V. Frangioni, MD, PhD, Cornelis J.H. van de Velde, MD, PhD, and Alexander L. Vahrmeijer, MD, PhD,* J Surg Oncol. 2011 Sep1; 104(3): 323-332., “The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery”

Contact Information

Further information or questions on our products, please contact us, E-mail: info_itnl@goryochemical.com